THERMOREGULATION PART I. FROM BASIC NEUROSCIENCE TO CLINICAL NEUROLOGY VOLUME 156

SECTION I. THERMOREGULATION SYSTEM
1. The thermoregulation system and how it works

SECTION II. THERMORECEPTORS
2. Peripheral thermoreceptors in innocuous temperature detection
3. Molecular basis of peripheral innocuous cold sensitivity
4. Molecular basis of peripheral innocuous warmth sensitivity
5. Peripheral and central determinants of skin wetness sensing in humans
6. Nociceptors. Thermal allodynia and thermal pain
7. Central thermoreceptors
8. Molecular Basis of Central Thermosensation

SECTION III. THERMOEFFECTORS
9. Brown adipose tissue as a heat-production thermoeffector
10. Shivering and nonshivering thermogenesis in skeletal muscles
11. Skin vasoconstriction as a heat-conservation thermoeffector
12. Cutaneous active vasodilation as a heat-loss thermoeffector
13. Sweating as a heat-loss thermoeffector
14. Panting as a heat-loss thermoeffector
15. Thermal comfort

SECTION IV. NEURAL PATHWAYS
16. Afferent pathways for autonomic and shivering thermoeffectors
17. Efferent neural pathways for the control of brown adipose tissue thermogenesis and shivering
18. Efferent thermoregulatory pathways regulating cutaneous blood flow and sweating
19. Central neural substrates involved in temperature discrimination, thermal pain, thermal comfort, and thermoregulatory behavior

SECTION V. THERMOREGULATION AS A HOMEOSTATIC FUNCTION
20. Body temperature and sleep
21. Skin Temperature, Sleep and Vigilance
22. Thermoregulation and the ultradian basic rest-activity cycle
23. Thermoregulation and age
24. Temperature and adaptive immunity
25. Interactions between body fluid homeostasis and thermoregulation in humans
26. Obesity and Thermoregulation
27. Thermoregulation and nausea
28. Neurogenesis in the thermoregulatory system

• Presents a clear, logical pathway from the fundamental physiology of thermoregulation, through neurobiology, to clinical applications and disease
• Enables researchers and clinicians to better understand the value of temperature measurement in disease and the use of temperature as a therapy
• Integrates content from a broad field of research, including topics on the molecular physiology of temperature receptors, to the management of accidental hypothermia

Authors
Andrej A. Romanovsky, Professor, Trauma Research, St. Joseph’s Hospital and Medical Center, Phoenix, AZ; Adjunct Professor, School of Life Sciences, Arizona State University, Tempe, AZ, USA