THOMPSON & THOMPSON GENETICS AND GENOMICS IN MEDICINE. 9TH EDITION

1 Introduction
2 Introduction to the Human Genome
3 The Human Genome: Gene Structure and Function
4 Human Genetic Diversity: Genomic Variation
5 Principles of Clinical Cytogenomics and Genome Analysis
6 The Chromosomal and Genomic Basis of Disease: Disorders of the Autosomes and Sex Chromosomes
7 Patterns of Single-Gene Inheritance
8 Complex Inheritance of Common Multifactorial Disorders
9 Genetic Variation in Populations
10 Identifying the Genetic Basis for Human Disease
11 The Molecular Basis of Genetic Disease
12 The Molecular, Biochemical, and Cellular Basis of Genetic Disease
13 The Treatment of Genetic Disease
14 Developmental Genetics and Birth Defects
15 Cancer Genetics and Genomics
16 Risk Assessment and Genetic Counseling
17 Preconception and Prenatal Screening and Diagnosis
18 Application of Genomics to Medicine and Individualized Health Care
19 Ethical and Social Issues in Genetics and Genomics
Epigenetics
Cases: Clinical Case Studies Illustrating Genetic Principles
Glossary
Answers to Problems
Index

Features:
• Comprehensive coverage of: genomes in biology and medicine; copy number and structural genomic variation; novel discoveries; latest technology; and new genetic diagnoses
• Over 40 clinical case studies, capturing the latest challenges of variable expression, pleiotropy, and complex disorders through new diagnostic strategies
• Full-color text, illustrations, updated line diagrams, and clinical photos
• End-of-chapter questions and comprehensive answers to challenge the reader to consolidate the material into practice and prepare for examinations
• USMLE-style and multiple choice questions available as part of the eBook
• An enhanced eBook version is included with purchase. The eBook allows you to access all the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud

New To This Edition:
• Updated and new clinical cases, supported with photography by the not-for-profit organization, Positive Exposure
• New content on growing role of sequencing and novel functional assays in diagnosis and screening of genetic conditions
• New chapter on Epigenetics
• Clearer and more precise terminology, in response to contemporary and evolving guidelines
• New sections describing the use (and need for) genetic information from diverse populations, including unique indigenous and founder populations, for diagnosis and management.