1: Introduction to Basic Immunology and Techniques, Neil D. Avent
2: Human Blood Group Antigens, Neil D. Avent
3: Haemolytic Disease of the Fetus and Newborn, Neil D. Avent
4: Clinical Use of Blood Components, Lionel Mohabir
5: Microbiological Testing of Blood Donations, Catherine Hyland, John Barbara, and Lionel Mohabir
6: Human Platelet Antigens (HPA) and Human Neutrophil Antigens (HNA) and their Clinical Significance, Geoff Lucas
7: Compatibility Testing and Adverse Effects, Malcolm Needs
8: Immune Mediated Red Cell Destruction, Malcolm Needs
9: Human Leucocyte Antigens (HLA) and their Clinical Significance, Neil D. Avent
10: Haematopoietic Stem Cell Transplantation and Stem Cell Plasticity, Ruth Morse and Saeed Kabrah
11: Tissue Banking, Richard Lomas, Neil D. Avent, and Vehid Salih
12: Quality Issues, Joan Jones
Biomedical scientists are the foundation of modern healthcare, from cancer screening to diagnosing HIV, from blood transfusion for surgery to food poisoning and infection control. Without biomedical scientists, the diagnosis of disease, the evaluation of the effectiveness of treatment, and research into the causes and cures of disease would not be possible.
The Fundamentals of Biomedical Science series has been written to reflect the challenges of practicing biomedical science today. It draws together essential basic science with insights into laboratory practice to show how an understanding of the biology of disease is coupled to the analytical approaches that lead to diagnosis.
Assuming only a minimum of prior knowledge, the series reviews the full range of disciplines to which a Biomedical Scientist may be exposed—from microbiology to cytopathology to transfusion science.
The science of transfusion and transplantation demands a multifaceted understanding of immunology, haematology, and genetics from the biomedical scientist. Transfusion and Transplantation Science synthesizes the essential concepts of these subjects and presents them within the practical framework of the hospital banking and transplantation centre, providing you with the knowledge and skills to specialize in this discipline.
• A blend of science theory and biomedical science practice make this series ideal for those seeking both the knowledge and skills to become proficient Biomedical Scientists
• Case studies and other examples enrich the text, firmly rooting it in the context of clinical and biomedical practice
• Self-test and discussion questions, with answers provided online, encourage students to analyze the text and develop their problem solving skills
• The book is augmented by an Online Resource Centre, which includes video interviews with practicing biomedical scientists and 'in the lab' footage showing biomedical science in practice
New to this Edition:
• A completely revised chapter on all human blood group systems, their antigens, genes, and function in the red cell, and including new developments in blood group genotyping.
• A new chapter on haemolytic disease of the newborn and fetus, including prenatal diagnosis, current clinical management, screening of D-negative mothers, and non-invasive prenatal blood grouping.
• A revised chapter on solid organ transplantation , including the clinical management of transplants, major rejection episodes, the management of transplantation by immunosuppression, and the potential of xenotransplantation to alleviate the shortfall of human organs.
• All remaining chapters have been revised and updated.
• Case studies have been extended to help foster an understanding of the diagnostic process, taking the reader through each clinical case from initial presentation to the interpretation of results.
Professor Neil Avent is Professor of Molecular Diagnostics and Transfusion Medicine at the School of Biomedical & Healthcare Sciences of Plymouth University. He has taught transfusion and transplantation to undergraduates since 1999 and to biomedical scientists at Masters levels.