TUMORS OF THE SACRUM. DIAGNOSIS AND TREATMENT OF BENIGN AND MALIGNANT TUMORS

1. Epidemiology of Bone Lesions of the Sacrum
2. Overview on Bone Sacral Tumors
3. Clinical and Neurological Manifestations of Sacral Tumors
4. Imaging of Sacral Tumors and Tumor Simulators: Experience of the Mayo Clinic
5. Imaging of Sacral Tumors: Experience of the Rizzoli Institute
6. Biopsy and Staging of Sacral Tumors
7. Histopathology of Sacral Tumors and Pseudotumors
8. Giant Cell Tumor of the Sacrum
9. Osteoblastoma of the Sacrum
10. Osteoid Osteoma of the Sacrum
11. Aneurysmal Bone Cyst of the Sacrum
12. Schwannoma of the Sacrum
13. Benign Cartilaginous Tumors of the Sacrum
14. Metastases of the Sacrum
15. Chordoma of the Sacrum
16. Osteosarcoma of the Sacrum
17. Ewing’s Sarcoma of the Sacrum
18. Lymphoma and Myeloma of the Sacrum
19. Chondrosarcoma of the Sacrum
20. Anatomy and Surgical Approaches to the Sacrum
21. Tumors of the Sacrum: Diagnosis, Management, and Surgical Techniques
22. Computer Navigation in the Sacrum
23. Sacral Biomechanics and Reconstruction
24. Soft Tissue Reconstruction Following Sacrectomy
25. Embolization for Sacral Tumors
26. Palliative Treatments for the Sacrum
27. Radiation Therapy for Primary Malignant Sacral Tumors
28. Tumors of the Sacrum: The Role of Chemotherapy

This book provides an up-to-date overview on the epidemiology, clinical presentation, and imaging characteristics of sacral tumors, discusses the available treatment options, and reports the published outcomes. The diagnostic roles of conventional radiology, CT, and MRI are thoroughly described and imaging appearances are compared with the histologic features. The coverage of therapeutic approaches includes chemotherapy, radiotherapy, radiosurgery, and surgery (partial or total sacrectomy and spinopelvic reconstruction). Special attention is paid to the specific anatomic constraints that make tumors in this region of the spine more difficult to manage effectively than those in the extremities and the mobile portions of the spine.
All components of the sacrum can give rise to benign or malignant tumors, which pose significant diagnostic and therapeutic challenges. Although these tumors are often diagnosed at an advanced stage, good clinical outcomes may be achieved if an aggressive multidisciplinary approach is used. This book will be of value for a range of practitioners; it will assist in prompt diagnosis and help to overcome lack of familiarity with the required treatment strategies.

Features
• Provides detailed guidance on diagnosis and treatment strategies
• Reports the experiences at the Rizzoli Orthopaedic Institute
• Written in cooperation with U.S. centers
• Highlights the importance of a team approach

Authors
1. Pietro Ruggieri, MD PhD. Department of Orthopedics and Orthopedic Oncology. University of Padova, Italy
2. Andrea Angelini, MD,PhD. Department of Orthopedics and Orthopedic Oncology. University of Padova, Italy
3. Daniel Vanel, MD. Department of Pathology. Istituto Ortopedico Rizzoli, Bologna, Italy
4. Piero Picci, MD. Laboratory of Experimental Oncology. Musculoskeletal Oncology,Istituto Ortopedico Rizzoli, Bologna, Italy