UTERINE CANCER. DIAGNOSIS AND TREATMENT

Uterine cancers are the commonest malignancies of the female genital tract in the developed world, and are increasing in numbers world over because of obesity and other life-style changes. Many of these malignancies are hereditary and thus, a better understanding of the genetic and molecular biology is needed. This would lead to appropriate treatment plan for improving the quality of life and long-term survival. This book addresses, in depth, all aspects of uterine malignancies covering both carcinomas and sarcomas. The book is divided into seven sections; the first two sections deal with epidemiology, molecular aspects, familial cancers and pathology and the later sections focus on diagnosis, imaging techniques and comprehensive management of both early stage and advanced cancers. Surgical techniques, adjuvant chemotherapy and radiotherapy have been covered in detail. Apart from the open surgical methods, role of laparoscopy and emerging role of robotic surgery in the contemporary management of endometrial cancers have been discussed. Written by authors with expertise in the field of gynecologic oncology from premier institutes, this book provides up-to-date information on best practice management of uterine malignancies.

Feature
- Covers both carcinomas and sarcomas
- Six sections dealing with epidemiology, molecular aspects, familial cancers, pathology, diagnosis, imaging techniques and comprehensive management
- Covers surgical management and chemotherapy and radiotherapy

Author
Dr.Shalini Rajaram, MD Director Professor Department of Obstetrics & Gynecology University College of Medical Sciences & Guru Teg Bahadur Hospital, Delhi, India Affiliations -Member, International Gynaecological Cancer Society(IGCS) Member, Asia Oceania Research Organisation on Genital Infections and Neoplasia (AOGIN) Member, Association of Gynaecologic Oncologists of India(AGOI) and Editorial Board Member of Indian Journal of Gynaecologic Oncology Reviewer, Indian Journal of Cancer -Member, FOGSI, AOGD, NARCHI Awards - Young Scientist’s Award for Research in Cancer Cervix, Assoc Gyn Oncologists, 1999 - President’s Prize for Best paper (Research in cancer cervix) at the Japan Society of Obstetrics & Gynaecology, Tokyo, April 2004 - RD Pandit Award for Best PG Thesis in India Awarded to her PG’s for Work in Cancer Cervix: 1999, 2002, 2005 Author of Books - Video Atlas of Surgical Techniques in Obstetrics & Gynaecology, 2009 - Ovarian Cancer: Contemporary and Comprehensive Management, 2009 - Practical Manual of Obstetrics & Gynaecology for PG Examination. Jaypee Brothers, Medical Publishers, New Delhi, 2009 - State-of the Art Vaginal Surgery, 2007 - ‘Non-Descent Vaginal Hysterectomy, 2006 - ‘Advances in Obstetrics & Gynaecology’(Vol I,II) 2005,2008 - ‘Current Practice in Obstetrics & Gynaecology’ 2000 - More than 100 Publications in National and International Journals - Well known for her Academic Skills as Writer, Speaker, Author, Editor. - Keen Laparoscopic, Vaginal and Oncosurgeon.

Table of contents (42 chapter)
1.Epidemiology of Endometrial Cancers and Uterine Sarcomas
2.Molecular Pathology and Cytogenetics of Endometrial Carcinoma, Carcinosarcoma, and Uterine Sarcomas
3.Hereditary Cancers of the Endometrium: HNPCC Syndrome and Beyond
4.Screening and Prevention of Carcinoma Endometrium
5.Clinical Evaluation of Abnormal Uterine Bleeding
6.Risk Factors, Diagnosis, and Staging of Endometrial Cancer
7.Imaging in Uterine Malignancy: Role of Ultrasonography, CT, and PET-CT
8.Magnetic Resonance Imaging in Endometrial Cancer
9.Steroid Receptors in Normal Endometrium and in Endometrial Cancer
10.Pathology of Endometrial Hyperplasia and Carcinoma
11.Pathology of Uterine Sarcomas
12.Prognostic and Predictive Factors in the Management of Carcinoma Endometrium
13.Surgical Anatomy of the Uterus
14.Endometrial Cancer Staging
15.Sentinel Node Evaluation in Endometrial Cancer
16.Surgery for Carcinoma Endometrium
17.Ovarian Preservation in Endometrial Carcinoma
18.The Role of Lymphadenectomy in Endometrial Cancer: The Mayo Clinic Experience
19.Extraperitoneal Laparoscopic Para-aortic Lymphadenectomy in Endometrial Cancer: Rationale and Surgical Technique
20.Role of Laparoscopic and Robotic Surgery in Endometrial Cancer: The Inevitable Evolution
21.Basics of Robotic Instrumentation and Robotic-Assisted Surgery for Endometrial Cancer
22.Adjuvant Radiation in Early-Stage Endometrial Cancer: Evidence, Principles, and Techniques
23.Therapeutic Options for Early-Stage Uterine Papillary Serous Carcinomas, Carcinosarcomas, and Clear-Cell and Mixed-Cell Histologies
24.Chemotherapy for High-Risk Early-Stage Endometrial Cancer: Current Evidence
25.Diagnosis and Management of Stage II Endometrial Cancer
26.Posttreatment Surveillance in Endometrial Cancer
27.Surgery for Advanced Endometrial Cancer
28.Systemic Treatment of Advanced Endometrial Carcinoma
29.Therapeutic Strategies in Recurrent and Metastatic Endometrial Cancer
30.Uterine Sarcomas: Risk Factors, Clinical Presentation, Diagnosis, and Staging
31.Surgical Management of Uterine Sarcoma
32.Role of Radiation Therapy in Uterine Sarcoma
33.Role of Systemic Therapy in the Management of Uterine Sarcomas
34.Surveillance of Uterine Sarcomas
35.Metabolic Syndrome and Endometrial Cancer
36.Management of Incompletely Staged Endometrial Cancer
37.Synchronous Cancers of the Ovary and Endometrium
38.Smooth Muscle Tumors of Uncertain Malignant Potential of Uterine Origin
39.Endometrial Cancers in Young Women: Conservative Management and Fertility Preserving Options
40.Hormone Therapy in Normal Postmenopausal Women and After Treatment for Endometrial Cancer
41.Effects of Tamoxifen and Other SERMs in the Endometrium and Follow-Up of Patients
42.Palliative Care and End of Life Options for Patients with Endometrial Cancer