HANDBOOK OF FORMULATING DERMAL APPLICATIONS: A DEFINITIVE PRACTICAL GUIDE

• Section I Preliminary Considerations and Selection of Raw Materials
1 Pre-formulation Design and Considerations 3
2 The Use of Thickeners in Topically Applied Formulations 29
3 The Incorporation of Delivery Systems into Topical Formulations: A Case Study on the Use of Salicylic Acid for Acne Treatment 45
4 Formulating Skin Care Products with Silicones: Approaches and Strategies 59
5 The Use of Corn-derived Ingredients in Personal Care Applications 115
• Section II Formulation, Processing and Production Techniques
6 Emulsions and their Characterization by Texture Profile Analysis 131
7 High Internal Phase Water-in-oil Emulsions 155
Introduction 155
8 Manufacturing Topical Formulations: Scale-up from Lab to Pilot Production 167
9 Foam: A Unique Delivery Vehicle for Topically Applied Formulations 233
• Section III Testing and Measurements Methods
10 Using Experimental Design to Optimize Formulations 263
11 Rheological Properties of Topical Formulations 287
12 Viscosity Measurement for Topically Applied Formulations 346
13 Fourier Transform Infrared (FTIR) Spectroscopic Imaging Analysis of Topical Formulations 369
• Section IV Sensory and Elegancy
14 Creating Appealing Topically Applied Formulations: Linking Physical Aspects to Marketing Psychology 381
15 The Use of Fragrance in Topically Applied Formulations 397
• Section V Stability and Preservation
16 Stability Testing for Topical Formulation Development 427
17 Preservation of Topical Formulations: An Historical and Practical Overview 463
18 Microbiological Stability for Skin Care Formulations 485
• Section VI Color Cosmetics
19 Lip Care Product Formulation Strategies 513
20 Formulation of Nail Care Products 539
• Section VII Sunscreens
21 Formulation of Sunscreens in the United States
22 Formulating a Day Cream with SPF: A Case Study 611

Glossary of Terms, by Chapter 635
Author Biographies 655

The conceptualization and formulation of skin care products intended for topical use is a multifaceted and evolving area of science. Formulators must account for myriad skin types, emerging opportunities for product development as well as a very temperamental retail market.
Originally published as “Apply Topically” in 2013 (now out of print), this reissued detailed and comprehensive handbook offers a practical approach to the formulation chemist’s day-to-day endeavors by:
• Addressing the innumerable challenges facing the chemist both in design and at the bench, such as formulating with/for specific properties; formulation, processing and production techniques; sensory and elegancy; stability and preservation; color cosmetics; sunscreens;
• Offering valuable guidance to troubleshooting issues regarding ingredient selection and interaction, regulatory concerns that must be addressed early in development, and the extrapolation of preservative systems, fragrances, stability and texture aids;
• Exploring the advantages and limitations of raw materials;
• Addressing scale-up and pilot production process and concerns;
• Testing and Measurements Methods.

The 22 chapters written by industry experts such as Roger L. McMullen, Paul Thau, Hemi Nae, Ada Polla, Howard Epstein, Joseph Albanese, Mark Chandler, Steve Herman, Gary Kelm, Patricia Aikens, and Sam Shefer, along with many others, give the reader and user the ultimate handbook on topical product development.